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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD1 All Species: 30
Human Site: T250 Identified Species: 55
UniProt: O14646 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14646 NP_001261.2 1710 196688 T250 K E D E E M K T D S D D L L E
Chimpanzee Pan troglodytes XP_517850 1710 196736 T250 K E D E E M K T D S D D L L E
Rhesus Macaque Macaca mulatta XP_001097125 1712 197047 T252 K E D E E M K T D S D D L L E
Dog Lupus familis XP_848459 1711 196992 T249 K E D E E M K T D S D D L L E
Cat Felis silvestris
Mouse Mus musculus P40201 1711 196392 T248 K E D E E M K T D S D D L L E
Rat Rattus norvegicus Q9JIX5 2581 290674 K545 P V V G K K R K R N T S S D N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513135 1807 208022 T251 K E D E E M K T D S D D L L E
Chicken Gallus gallus B6ZLK2 1719 197507 T246 K E A E E T K T D S D D L L E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 K615 N R Q V K R K K Y T E D L D I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KU24 1883 211809 T289 E A S E D E A T D S E D L L E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 K325 I V E E E P A K A N M D Y C R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387 C67 N L V S C N T C T Y A F H A K
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 D151 D D L L E S E D D Y G S E E A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.3 98.3 N.A. 95.7 23.3 N.A. 88.6 92.4 N.A. 23.6 N.A. 45.6 N.A. 26.3 N.A.
Protein Similarity: 100 99.8 99.8 99.3 N.A. 97.9 38.9 N.A. 91.6 95.9 N.A. 38.8 N.A. 62.1 N.A. 43.8 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 100 86.6 N.A. 20 N.A. 53.3 N.A. 20 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 100 86.6 N.A. 40 N.A. 73.3 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.9 31.1 N.A.
Protein Similarity: N.A. N.A. N.A. 42.2 49.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 0 16 0 8 0 8 0 0 8 8 % A
% Cys: 0 0 0 0 8 0 0 8 0 0 0 0 0 8 0 % C
% Asp: 8 8 47 0 8 0 0 8 70 0 54 77 0 16 0 % D
% Glu: 8 54 8 70 70 8 8 0 0 0 16 0 8 8 62 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 54 0 0 0 16 8 62 24 0 0 0 0 0 0 8 % K
% Leu: 0 8 8 8 0 0 0 0 0 0 0 0 70 62 0 % L
% Met: 0 0 0 0 0 47 0 0 0 0 8 0 0 0 0 % M
% Asn: 16 0 0 0 0 8 0 0 0 16 0 0 0 0 8 % N
% Pro: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 8 8 0 8 0 0 0 0 0 8 % R
% Ser: 0 0 8 8 0 8 0 0 0 62 0 16 8 0 0 % S
% Thr: 0 0 0 0 0 8 8 62 8 8 8 0 0 0 0 % T
% Val: 0 16 16 8 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 16 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _